Sentence examples for constraining the binding from inspiring English sources

Second, they constrain the seed match alignment, without constraining the binding energy for the match, to belong to one of the five seed classes of miRNA seeds, as defined in [ 4].

This location of the first actin and bound W motif constrains the binding site of the C motif to subunits Arp2 and ARPC1, from where the A motif can reach subunits Arp3 and ARPC3.

It seems that the more constrained the binding mechanism, the lower the bound.

The extended vs the more compact conformation of the tandem tudor domains would place the binding partners of individual tudor units at different geometric arrangements, constraining the interactions of binding partners with the tudor domain proteins, as well as those between themselves and with downstream targets, hence determining the biological properties of the tudor domain proteins.

These functional differences are likely due to the unique structural features of each cHES6 protein, in particular the different sizes of the loop region within the bHLH domain, which is known to constrain the DNA-binding capacity of HES proteins [9].

The shadow price will be zero for a non-binding constraint since its right-hand side is not constraining the optimal solution [42].

Second, AFF4 binding to Tat-P-TEFb indirectly constrains the TRM conformation, increasing the binding affinity for TAR 30-fold.

Also, it appears that evolution has constrained the function of some binding proteins not simply through sequence conservation but through conserving regions to remain disordered.

Structure-based modeling of this putative state [ 318] suggests that the power stroke is not a reversal of the recovery-stroke, because the tight actin-binding constrains the relative motion of the upper and lower 50 K domain [ 59].

Such interactions constrain the spacing and orientation of the binding sites of the individual subunits.

This mechanism does not require any protein protein interactions and would not be expected to constrain the spacing and orientation of the binding sites of the cooperating TFs.