Your English writing platform
Discover LudwigSuggestions(1)
Exact(5)
FBA was also used to predict essential reactions by constraining reactions to have zero flux and maximizing growth rate.
EFMs are generated by constraining reactions to zero flux; EFMEvolver utilizes a genetic algorithm [ 18], while the k-shortest EFM utilizes a binary solver [ 21] for this purpose.
The combination of nesting species, assigning attributes, and constraining reactions according to these attributes is crucial in achieving the desired expressiveness.
The effect of genetic changes such as gene deletion can be simulated by constraining reactions associated to gene of interest to be zero [ 45].
Nesting species, assigning attributes to these species, and constraining reactions according to attributes have been identified as further essential ingredients in supporting multi-level modeling.
Similar(55)
I asked how important gene linkage is in constraining reaction evolution by examining the most highly constrained reaction pairs and how closely together their encoding genes are linked in a genome.
In all of these methods, regulatory rules can only constrain reactions to one single flux value.
For more tightly associated reaction sets (very small P-values), this bias towards constrained reactions in the same pathway increases.
Metabolic fluxes of these constrained reactions were allowed to be reconciled within the range of their standard deviation (Table 1).
The Yeast 5 GEM has 326 more directionally constrained reactions than Yeast 4 (69% of all reactions in the Yeast 5 GEM are constrained, compared to 55.6% in Yeast 4).
Based on these analyses, the grouping reaction (GR) constraints that constrain reactions to co-carry fluxes altogether regardless of the condition were incorporated into the E. coli genome-scale metabolic model.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com