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Exact(30)
The P1′ side chain sterically blocks the His 64 imidazole from adopting the outward χ1 = −60° rotamer, constraining it toward its observed position where it is adjacent to Ala 32 and adjacent to the anion site.
I don't know exactly what was in the Florida Supreme Court's mind, but I think that, in general, what the Florida Supreme Court made quite clear is that the thing that was constraining it was the desire to fit its remedy within the safe harbor provision.
Or constraining it somewhat.
It's uncomfortable, constraining, it might be better to let go.
Reich had some grasp of the creativity of sexual desire, and the cost of constraining it.
She seems to sprawl imperiously, as if she had decided to liberate her massive body from something that has hitherto been constraining it.
Similar(29)
Saudi Arabia could break its teeth there if the U.S. does not constrain it.
Continue to constrain it and they will go up.
We can't rule out such a bizarre scenario, but we can strongly constrain it.
They can make the thing you're trying to do easier, but they simultaneously constrain it".
The last administration did not feel so constrained; it merely took the costs "off budget".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com