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The findings of Nitta et al. also indicate that transcription factors do not evolve to recognize subtly different DNA motifs, but instead appear constrained to recognize the same motifs.
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Finally, constraining Anticheta + Renocera to be monophyletic and further constrained to be a separate lineage outside of the currently recognized tribes produced a tree that was not significantly worse than the unconstrained tree (Table 2).
Bush was constrained to take exception to this publicly.
(Mahler, one feels constrained to add, means painter in German).
Before this, were you constrained to singing in the shower?
Or can be constrained to do so.
aElasticity constrained to −0.10.
In Drosophila studies, "bottom" was constrained to 0, while the "top" was not constrained.
No calibrations were constrained to be monophyletic.
The intercept was constrained to equal zero.
Given that the catalytic rate constants of these enzymes, at 1 5 min−1 [ 37, 40], are of the same order as those observed for catalytic RNA [ 61], these enzymes may be more constrained by the need to recognize pre-crRNA specifically than by a requirement to turn over rapidly.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com