By constraining them to come from a common distribution, individual-level estimates are influenced by measurements from other such individuals (shrinkage to the population mean, Gelman and Hill 2007).
The only downside, for me, was having to wait (some mornings) for tides to come in -- and being constrained to stay on the beach by the group van.
While his book was a Herculean feat, Mr. McClatchy was not constrained by having to come up with translations that matched the music.
The alternative view has been argued by George Soros, who believes that the financial crisis is the culmination of a 25-year credit bubble and that credit, economic activity and equity returns will be constrained for decades to come.
WD-40 and hairspray come in spray bottles, so be sure to apply the product from a close range, keeping the spray area constrained to the stain.
Bush was constrained to take exception to this publicly.
(Mahler, one feels constrained to add, means painter in German).
aElasticity constrained to −0.10.
So far PIMiM only uses expression values in a regression setting (although we constrain the regulators to come from the sequence-based predicted set, the regression model itself does not directly encourage the assignment of miRNA and predicted mRNA targets to the same module).
Even if the economy were, miraculously, to bounce back and grow during 2010, the state of the public finances is so dire that government expenditure will be heavily constrained for several years to come.
