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The more tightly constrained the problem being simulated, the more the semantics of the problem can be exploited to increase computational efficiency.
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To ensure aesthetic quality and reduce the search space, current approaches may constrain the problem to less flexible layouts and well-behaved content.
However, when the ambition is to develop a tool that can be applied in real-life conditions, it is necessary to constrain the problem.
Using a priori information about the source distribution can be beneficial for constraining the problem and improving the reconstruction.
Specifically, it does not demonstrate that the additional MILP constraints do not over-constrain the problem and eliminate some non-loop containing solutions.
Here we apply Gordan's theorem from linear algebra to prove for the first time that the constraints added in loopless-COBRA do not over-constrain the problem beyond the elimination of the loops themselves.
An underlying assumption of a biomedical model of the problem constrained the communication between clinicians and parents in these consultations.
This is attributed to the limited amount of measured data used to constrain the inverse problem.
Read-pairs were tested separately to check if they could constrain the scaffolding problem by defining a unique path between two contigs.
Finally, we apply our results to the constrained minimization problem and the split feasibility problem as well as the minimum-norm fixed point problem for pseudocontractive mappings.
We solve the constrained optimization problem using the Lagrange multiplier method.
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