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This implies that lineage specification of Treg cells is governed by a specific evolutionarily constrained small set of regulatory elements, which is in contrast to the more plastic conservation of global genome-wide regulatory network architectures (Stergachis et al., 2014; Vierstra et al., 2014).
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Nevertheless, moissanite and a panoply of metals (Fe, FeNiSi-alloy, Ti) and Fe-silicides occur in these xenoliths but are constrained to small voids.
The representation is normally constrained to small structures, or parts of a larger structure, to prevent a preponderance of invalid designs.
In mobile data networks, the communication bandwidth is limited and the wireless handsets are constrained by small display, powerless CPU, limited memory, and unhandy input/output interface.
This result will hold for situations in which the totally enclosed water phase is constrained to small deformations by virtue of its confinement.
By means of CT scan profiles of the macro-plug, thin section, and Hg injection technique we also get knowledge of the fact that abundant invisible microfractures are embodied in core samples from the formation, and though the pore radius of the formation rock is relatively large (25 30 μm), its connectivity is constrained by small throat radius (3 5 μm).
Previous attempts at global metabolic characterization of the date metabolome were constrained by small sample size and limited geographical sampling.
Although the incidence of cancers will increase as the cohort ages, currently we remain constrained by small numbers of cases for many tumor sites.
Subgroup analyses of incident breast cancers were constrained by small numbers, and diagnoses not reported by participants would not have been captured.
The majority of studies that have explored caseload midwifery to date have been constrained by small numbers of midwives and have been conducted at a single time point at a single site.
The percentage of Oil Red O positive hBMCs and hPDCs was higher in cells constrained on small fibronectin islands as compared to cells patterned on large islands (Fig. 5C).
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