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Waterloo International Terminal (London, 1993) Critically acclaimed station squeezing a sinuous snake of rail facilities into a highly constrained site.
Retrofit projects possess unique characteristics in comparison to traditional demolition and new builds such as partial operation of buildings, constrained site spaces and limited access to as-build information.
With purifying selection of this magnitude, it is approximately 9 million times more likely that a newly arising mutation at a neutral site will eventually rise to fixation than a newly arising mutation at a selectively constrained site.
"We worked on a constrained site in downtown Salem," Mr. Safdie explained.
In fact the final product is quite efficiently tucked away on a tricky and constrained site.
Allocation of funds towards provision of transportation and affordable housing infrastructure and/or mitigation must be balanced against design and constructability decisions (constrained site construction and demolition challenges, quality of building materials, lighting, etc)., allocations of uses, parking and open/street spaces and vegetation.
Similar(53)
If natural selection biases codon usage to enhance the accuracy of translation then synonymous codons corresponding to the most abundant tRNA should be favored at functionally constrained sites than at the less constrained ones (Akashi 1994).
The remaining constrained sites retain function and evolve at the same dependent rate in all groups.
Overall, SCPE outperforms JTT in the description of sequence patterns observed in structurally constrained sites.
While conserved, even functionally constrained sites have varied since the Eukarya split.
Depending on the orientation of functional selection, constrained sites will not always appear to be constrained and can even show less conservation than unconstrained sites.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com