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For many therapeutic applications, it is desirable to affect neurons promptly (e.g., to terminate epileptic seizures), in a regionally constrained manner to reach maximum on-target effects and reduce effects on unintended brain networks4,5.
Motif enrichment analysis of ChIP-seq data sets indicated that sequence-specific TFs can be recruited in a spatially constrained manner around MyoD1-binding sites.
In a constrained manner we argued back and forth.
Another adviser said Mr. Bush, by nature, adopted a more formal, constrained manner in public.
Levison believes that when the government was faced with the choice between getting information that might lead it to its target in a constrained manner or expanding the reach of its surveillance, it chose the latter.
Moreover, the interleaving of formal and semantic rules along a single inheritance path presents a novel way to model derivational relations in a constrained manner.
Similar(49)
The evolution of serial homologs may be influenced by the sharing of developmental genes and fitness trade-offs for the organism (Boyden 1947; Wagner 2007), such that serial homologs instead evolve in a constrained, dependent manner.
In many cases it may actually commit us to publicly intelligible values that we take our commitments to embody an aspect that may constrain the manner of our practical deliberation and the way in which we can pursue our commitments (Varga 2011a,b).
Among those are trade-offs between different ways an organism utilizes resources, and these trade-offs can constrain the manner in which selection can optimize traits.
Because India has been constrained in this manner, its economy has remained relatively undamaged by the global financial meltdown.
The Walking Dead's problem is that its possible narrative moves are constrained in a manner that more open-ended franchises are not (that's why, say, Coronation Street, set in a Manchester street, or Grey's Anatomy, set in a Seattle hospital, look as though they could carry on forever, changing characters and storylines with an abandon denied The Walking Dead).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com