A particularly ambitious recent example is the Retropath tool for the principled design of entire metabolic circuits [ 44 ], based on constraining information about the metabolic capacities of the envisaged host organism (chassis) and the scope of available chemical reactions.
Electoral accountability may therefore be constrained even when information about representative misconduct is easily available and clearly influences voter perceptions.
Preferentially, molecule target lists would be further constrained by information of taxonomy and organs.
Also, research within these populations has also been constrained due to scarce information about cultural differences on attitudes toward cosmetic surgery and their relationships with body image.
Consequently, students who attend low-quality schools, are financially constrained, and have limited information about how the admissions process works or about financial aid opportunities are at serious disadvantage with respect to enrolling in selective colleges (Winston and Hill, 2005; Owings et al., 1995; Pallais and Turner, 2006).
Figure 1 Time-constrained information cascade.
However, the simple scaling up of such results to explain conditions on a large field scale, across agricultural landscapes under varied management scenarios, or across landscapes made up of different types of ecosystems (agricultural, grassland, forest), is very much constrained by a lack of information about the spatiotemporal distribution of earthworm populations.
An important feature of our method is that it cannot only detect constrained elements, but it also provides information about the potential functional constraints associated with each base of the constrained sequences.
Moreover, the system can be under uncertainties, information about which is constrained as well.
We were however constrained by the lack of additional information about temperature measurements at depth so we compare our calculated heat flow result with the value expected in Precambrian basement complex.
