DOI: http://dx.doi.org/10.7554/eLife.05462.012 An active mode of dosage compensation is predicted to constrain expression in the face of underlying gene amplification, thereby buffering CNV.
"It is, therefore, for the State of the Islamic Republic of Pakistan to ensure that no innocent person is compelled or constrained to face an investigation or a trial on the basis of false or trumped-up allegations regarding commission of such an offence," the ruling continued.
In real world, sensors are usually embedded on board a moving vehicle, and consequently, the embedded systems are constrained to face the hard real-time constraints imposed by moving vehicle applications.
But the Senate intelligence committee made public a C.I.A. assessment that Iraq appeared to be stopping short of mounting terrorist attacks against the U.S., yet could become much less constrained if facing a U.S.-led force.
This was the message from Tokyo, Beijing and Washington, where policymakers felt constrained in the face of Europe's procrastination.
Constrained resources, which face all start-ups, force ingenuity and frugality, traits which put any company on solid ground during its early stages.
Unless they can upgrade their knowledge and skills -- and, in some cases, move to a new industry or location -- they face constrained economic opportunities.
39 Here treatment choices are more constrained in the face of multiple drug-drug and drug-disease interactions, and effective diabetes treatment might require more global treatment optimisation.
In this method a new penalization strategy was introduced in order to extend the ACO framework to face constrained optimization problems.
