"I think it's mainly people who know the agency but are no longer constrained by obligations to the president.
Unfortunately, one of the sharpest lessons of the 20th century is that men who have convinced themselves that they know what their country needs are all too likely, unless constrained by an obligation to consult the people at regular intervals, to behave just as badly as Messrs Fujimori, Yeltsin and Sharif did or even worse, because the need for the people's consent has never occurred to them.
In this case, further diversification of carotenoid biosynthesis is constrained by the obligation of this lineage to provide the apocarotenoid retinal, a β-carotene cleavage product, as a cofactor critical to proteorhodopsin function [11].
Evolution of this carotenoid biosynthetic pathway, therefore, does not principally involve an expansion of carotenoid structural diversity (being constrained by the obligation to interact productively with the photosynthetic reaction center) but instead involves expansion of the taxa in which the pathway occurs in conjunction with purple bacterial phototrophy.
Preschoolers universally recognize that one's choices are not always free – that our decisions may be constrained by social obligations to be nice to others or follow rules set by parents or elders, even when wanting to do otherwise.
In all such relationships, a parent, lover or friend will sometimes find himself tightly constrained by certain obligations and commitments.
If you have similar ambitions constrained by moral obligations, there are many other means of earning a living that are more lucrative than lawyering.
Another concern is that students who do attend such institutions feel constrained by their debt obligations in making postgraduate career choices.
Second, she contends that group justification is constrained by certain epistemic obligations that arise from professional relationships among group members, a complication that the aggregative account lacks the ability to accommodate.
In addition, women who joined the project were often constrained by marriage and family obligations.
Three themes were identified: a) Supporting one's wife; b) Marital needs and obligations; c) Constrained by a culture of destiny and shame.
