On the one hand, we want to calculate the constrained accuracy given the partial structures and, which is defined as (8) On the other hand, we have to find a combined score for the partial structures and, and the interaction σint to evaluate the quality of an predicted interaction.
When the entire window was constrained accuracy was much higher (supplementary fig. S3 A, Supplementary Material online), typically ∼90% or greater (supplementary table S6, Supplementary Material online), with the one exception being cases where the mutation rate was low in these cases unselected regions were often misclassified as selected.
Sampling intensity and taxonomic expertise severely constrain accuracy of seaweed mapping and floristic data, as well as notions of abundance and rarity.
For example, although the TOWRE is designed to tap both fluency and accuracy, performance is mainly constrained by accuracy in early childhood, whereas fluency becomes a more important factor in determining performance later on (Torgesen et al., 1999).
On the concatenated alignment, we apply an adapted PETfold model that can handle fixed partial structures σp1 and σp2 from the first step by constrained expected accuracy scoring, which is an extension of PETfold's maximum expected accuracy scoring for constrained folding.
For sprays, as described by a kinetic disperse phase model strongly coupled to the Navier Stokes equations, the resolution strategy is constrained by accuracy objectives, robustness needs, and the computing architecture.
The constrained expected accuracy structure σint is calculated by a Nussinov-style algorithm and might contain both intra-molecular as well as inter-molecular base pairs.
The final prediction of intra- and inter-molecular base pairs consists of the reliabilities computed from the constrained expected accuracy scoring, which is an extended version of that used for individual multiple alignments.
This is in agreement with Seemann et al. (2010), in which we showed that the structural mass of intra-molecular partial structures has to be high to support the constrained expected accuracy scoring.
These azimuthal gap values are sufficient to constrain location accuracy for these events as the largest azimuthal gap is, at worst, 180° as also specified by several authors such as Engdahl et al. (1998, 2007).
Such verification results help us understand and constrain the accuracy and reliability of ash transport models and it is of enormous relevance for designing future operational mitigation strategies at Volcanic Ash Advisory Centers.
