We reasoned that if IICR constrains the diffusion of GABAAR through PKC-dependent phosphorylation, the blockade of PKC should mimic the effect of the IICR inhibitor 2APB.
Altogether our results show that the IICR-signaling pathway constrains the diffusion of GABAAR during basal activity, maintaining a stable pool of GABAARs at inhibitory synapses.
We considered extracellular matrix formation as a specific defense mechanism, however it is true that it also constrains the diffusion of secreted materials.
Thus, our data establish that non-chromosomal DNA circles and NPCs reciprocally constrain the diffusion speed of each other, in a SAGA-dependent manner.
The data on energy spectra and anisotropy of very high energy protons, nuclei and electrons, and the astronomical data on supernova remnants, the potential sources of cosmic rays, are used to constrain the value of the cosmic-ray diffusion coefficient and its dependence on energy.
Based on a nonlocal patch-based strategy, the proposed method uses a non-diffusion image (b0) to constrain the reconstruction of DW images.
Using Exploratory Spatial Data Analysis (ESDA), we find that the diffusion of political change is constrained by infrastructure: political change diffuses from one municipality to the next only when connected by a major highway an important distinguishing feature in landscapes with difficult terrain.
In a parallel fiber arrangement of a white matter tract, the diffusion of water molecules is directionally constrained, resulting in a high FA value.
These patterns both enable and constrain people's actions, which means that there are winners and losers in the diffusion of modern sports from Europe and North America to the rest of the world.
