The program is broad enough that documents indicate that analysts are asked to constrain searches to no more than 1,800 phone numbers at a time.
Since for most alignments the number of phylogenetically informative positions is low with respect to the number of sequences, trees contain a high number of unstable nodes and therefore it was not possible to constrain searches for convergence with a lower threshold value.
Software Product Lines Engineering SPLEE) consists in optimising those large and highly constrained search spaces according to multiple objectives reflecting the preference of the different stakeholders.
Using symmetry constrained search and Nudged Elastic Band method, we characterize the transition states for an oxygen anion moving into a nearby oxygen vacancy site that is surrounded by different cations and find the activation energies to vary in the range of 30 50 kJ/mol in good agreement with experimental data.
We also tested for monophyly of all asexual respectively sexual species using the same approach (constrained search with asexuals resp. sexuals as a monophyletic clade).
In general, computational prediction of miRNAs uses a highly constrained search space by setting fixed values to parameters like AU content, MFEI and the length of the pre-miRs [ 12, 13, 15, 16].
Since wQMC does not constrain the search space, this means that wQMC can find trees with better quartet scores but which are outside the constrained search space, and that constraining the search space seems to be beneficial with respect to topological accuracy.
ASTRAL and ASTRAL-2 differ in how they constrain the search space (ASTRAL-2 searches a larger part of tree space than ASTRAL) and how they are implemented (ASTRAL-2 is faster).
It may simultaneously constrain their search for SRHR information, negotiation of contraceptive use, or search for adequate and safe services if they become pregnant out of a fear of being perceived as promiscuous.
In a nutshell, instead of searching for a general nonnegative function, we can constrain our search to functions that can be parameterized as sums of squares of polynomials.
