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Strategic planning documents may have a bureaucratic origin, when they represent an administrative constrain imposed by law or by a higher level of Government.
The higher MICs could be explained by the technical constrain imposed by the mutant selection method [ 22] in which the active multiplying cells need to be grown in presence of triclosan concentrations sufficient to isolate resistant mutants from wt strains.
This observation led us to hypothesize that the recently recognized autophagy-promoting function of PED/PEA-15 is necessary for the myogenesis constrain imposed by TGF-beta1, as TGF-beta1 has also been very recently shown to induce autophagy in non-muscle cells.
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Several delegates reminded the group that constrains imposed by grant makers and regulators – such as holding high capital reserves - present a major challenge.
Thus, the conformational constrains imposed by these local and global modifications affect both the pharmacokinetic and pharmacodynamic properties of the parent peptide.
Considering that space heating is the major energy consuming activity in the Greek building sector and that the environmental constrains imposed by the Kyoto protocol will be met only with difficulty, if at all, a strategy concerning the developments in space heating seems to be necessary.
Communication protocols used in traditional control systems are required to comply with the constrains imposed by industrial standards (e.g., to cover regulation roles such as delay and faults).
Moreover, the setting of the data rate (based on the MCS configuration) in the multicasting scenario is dictated by constrains imposed by the critical client nodes of a multicast transmission, i.e. the most interference-prone client nodes within the multicast group.
These conformational differences are probably a result of small changes in the electrostatic interactions between amino acid residues rather than by 'gross' conformational changes caused by hinge flexibility or by structural constrains imposed by the oligosaccharide moieties [31], [32].
This could help to determine the putative constrains imposed by TADs onto the 3D dynamics associated to Hox gene collinear activation.
Because of the difficulty in using conventional breeding for banana improvement, molecular biotechnology offers great hope for improving banana for enhanced disease resistance and for other agronomically important traits by overcoming the constrains imposed by the sterility of cultivated banana.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com