The tested cell-cycle mutants had a general trend of constitutive CIN rates very different from the environment-modulated genome instability seen in rho0 cells.
In another essay popularly associated with his name, Oruka identified four main trends to be constitutive of African philosophy, namely (i) African ethnophilosophy, (ii) African nationalist-ideological philosophy, (iii) professional African philosophy, and of course, (iv) the African Sage philosophy under consideration here.
The gene expression was constitutive in Pokkali, thus showing a uniform trend.
In contrast to patterns displayed by AHR core-response genes, most of our constitutive candidates appear to exhibit up-regulatory trends in the AHR-less-active animals (p = 0.0014, 95% confidence interval: 0.58-1.00, one-sample prop test).
More precisely, the predictions provided by these criteria, for each constitutive model studied, are compared with the experimental trends observed in metallic materials for such loading conditions.
These trends apparently correlate with the extent of constitutive expression in untreated atm and atr, as clusters M1 and M2 were large, whereas cluster R1 was single and included a small set of genes (Fig. 7).
The final linear trend depends on the plastic potential of the constitutive model (i.e., is a function of the strain hardening).
A similar trend in protein accumulation was observed for the constitutive expression of the same transgenes in newly-established suspension cultures whose growth in liquid medium had not been completely stabilized (data not shown).
Comparisons with sensitivity data for low-speed spinning conditions demonstrate that the incorporation of crystallization effects leads to improved predictions of the magnitude and trends of the perturbation frequency dependence for both constitutive equations.
This can be done not only for vertebrates, where evolution of the exon-intron structure is dominated by the exon dynamics [ 35], but also for (dipteran) insects, where intron insertion and loss play an important role, while the general trend of lower conservation of alternative sites and exons compared to constitutive ones is the same as in vertebrates [ 11].
Based on the trends established from the analysis of housekeeping genes, it is apparent that constitutive expression requires many of the elements of the core promoter in various combinatorial complexities with various UTR structural features and a plethora of cis-elements involved in developmental and environmental signal perception.
