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In adult cartilage, proliferation is limited to pathologic conditions, while constitutive prevention of apoptosis is a necessity to withstand stressors like mechanical forces, reactive oxygen species and cytokine exposure [ 6- 8].
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With additional experiments, these authors concluded this decrease was due to interactions with constitutive Hsc70 and the prevention of protein misfolding.
Recently, an increasing number of studies have focused on the use of previously-identified risk factors and biomarkers (e.g., one or more constitutive SNPs (single-nucleotide polymorphism)) for cancer prevention or for pathway-targeted therapy development [ 6, 7].
Furthermore, the Peace and Security Protocol of 2002 (AU 2002), which derives from the Constitutive Act of the African Union, provides for the Continental Early Warning System for conflict prevention (AU 2000) and could be integrated with the early warning systems for DRR, including Famine Early Warning Systems.
We chose to investigate the COX-2 inhibitor in vivo with the hypothesis that preserving the COX-1-mediated constitutive role, while inhibiting the induced COX-2 activity, would optimize OA treatment and prevention.
Prevention of NE differentiation by EGF is mediated by a MAPK-dependent mechanism, requires constitutive Akt activation.
Constitutive phosphorylation of Akt leads to activation of downstream substrates involved in cell cycle regulation and apoptosis prevention [ 3].
The development of new chemokine‐based strategies for the prevention and treatment of inflammatory bowel disease (IBD) requires the ability to differentiate homeostatic chemokine signals responsible for constitutive immune surveillance from those that balance the function of inflammatory leukocyte subsets.
Crime prevention.
Such action would constitutive playing from the wrong place.
This constitutive vagueness has troubled climate negotiations ever since.
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CEO of Professional Science Editing for Scientists @ prosciediting.com