At this stage, the main constitutive equations have been presented, and this section is devoted to the presentation of relationships governing the evolution of physical properties with temperature, porosity, and pressure.
In macrophages and dendritic cells, which display high levels of constitutive macropinocytosis, macropinocytosis plays a central role in antigen presentation [1] [5].
The results presented here delineate constitutive pathways of MHC-I intracellular transport in DCs, and illuminate the nature of the intracellular compartments of DCs where peptides from exogenously-derived antigens are loaded for cross-presentation.
Oral tolerance relies on presentation of the relevant peptides by constitutive mucosal dendritic cells (DCs), with the capacity to regulate pathogenic T cells by deletion, immune deviation or through Treg-mediated suppression.
OX40, 4-1BB, CD27, and DR3 co-stimulatory molecules are constitutively expressed on Tregs and are either constitutive on conventional CD4 and CD8 T cells or induced usually within 24 hours after antigen presentation.
The genetic analysis, clinical presentation, and familial history are indicative of a constitutive ADAMTS-13 deficiency in patients A, B, C.> -wrap-foot> Deleterious polymorphism are in italic [ 22] Abbreviations: homozygous, Hm; heterozygous, Htz.
Since DCs are constitutive expressors of LMP7, this suggests that the cells responsible for antigen presentation during chronic infection could include other APCs or infected cell populations.
We conclude that, although immunoproteasomes can increase the generation of peptides appropriate for MHC class I presentation, they do not degrade ubiquitinated proteins more efficiently than constitutive particles.
Although it is common in philosophy to associate sciences with theories, such that the individuation of a science is dependent on a constitutive theory or group of models, it is uncommon to find presentations of developmental biology that make reference to a theory of development.
Elegant experiments in mice expressing transgenic Ag controlled by tissue-specific promoters have shown that, in normal conditions, constitutive migration of APC from peripheral tissues to draining lymphoid organs, results in presentation of tissue-derived Ag to T cells [ 45, 46].
