Affymetrix gene chip analyses were performed with mouse Set430_A arrays for the constitutive experiment or mouse Set430_2.0 arrays for the conditional experiment.
Notably most of the down-regulated genes in the conditional experiment are expressed from CpG island promoters (48/57), particularly in the group that overlapped with the constitutive experiment (23/24), which are most likely to be directly regulated by Mll2.
In order to study cyclic performance of high-strength structural steel and establish an appropriate constitutive relationship, experiments were carried out on seventeen Q460D steel specimens subjected to different loading patterns.
For the axisymmetric contraction and expansion passages with different geometry ratios, the results obtained are compared to available constitutive models and experiments.
A comparison of predictions based on the proposed frame-independent constitutive equation with experiments shows that the model is able to describe the rate dependent behaviour of the elastomeric foams examined.
Fig. 6D shows that, in four different experiments, constitutive release of CX3CL1 by HK and EF cells was increased significantly upon stimulation with TNF for the HK cell line (P = 0.028) and with IFN-γ for the EF cell line (P = 0.026).
Whilst in our experiments, constitutive expression of Pax3 or Pax7 did not prevent expression of MyHC or fusion into syncytia, the resultant myotubes had a significantly smaller diameter, showing that ectopic Pax3 or Pax7 restricts myoblast accretion and/or myotube growth.
These observations are in contrast to constitutive FUS3 misexpression experiments, which result in storage reserve accumulation in vegetative tissues.
In laboratory experiments, constitutive activation of the Ras signalling pathway has been identified as essential for cellular transformation [ 30].
