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As we have highlighted in the accompanying manuscript, serum levels of kynurenine metabolites may roughly mirror CNS levels because the constitutive action of the kynurenine pathway is low in the CNS, and at least KYN and 3-HK of peripheral source can cross the blood-brain barrier and fuel the pathway in the brain parenchyma [16].
In order to be effective as a buffering molecule, the affinity of a cAMP sponge should be somewhat less than the resting free levels of cAMP (maintained by the constitutive action of PDEs), otherwise the buffer molecule would be saturated prior to stimulation.
In these cells, green fluorescence is also detected in association with the parasite, probably because of constitutive action of the promoter that leads to overproduction of the protein and its accumulation in the parasite during blood stage growth.
However, our findings do not provide any new information for the debate on the ligand state of the putative ancestral steroid receptor before the deuterostomes and protostomes have separated, which hypothesizes either a ligand-regulation, a sensory function or a constitutive action [ 96, 97].
Similar(56)
This otherwise morally legitimate judicial process may be corrupted, if one or more of its constitutive actions are not performed in accordance with the process as it ought to be.
A new concept in G protein coupled receptor (GPCR -mediated druGPCR -mediatede occurrence of constitutive activity of GPCRs in the absence of agonist stimulation.
He depicts that battle with care and cleverness but without imagining that what goes through a person's mind is as real, as constitutive of the action, as what's visible from the outside.
Merleau-Ponty argues in favor of the constitutive role of action for consciousness in general.
For that would amount to a viciously circular and vacuous specification of the constitutive aim of action.
They maintain that perception can also depend in a noninstrumental or constitutive way on action (or, more generally, on capacities for object-directed motor control).
For actions like those of Galahad we look in vain for justifying reasons but it is often claimed that the attributability of explanatory reasons is constitutive of intentional action as such.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com