Sentence examples for constitutional alteration from inspiring English sources

Public interest in the case took hold, and it fed into the enthusiasm for the 1967 constitutional alteration giving the federal government power to make laws concerning Indigenous Australians, which until that point had been a state responsibility.

By far, his most important constitutional alteration was his creation of a bureaucratic apparatus, which included a fixed gradation of clearly defined offices, and a corresponding order of promotion.

Seven articles described CGH in mOGCTs, with the exclusion of repeatedly published cases and case reports with constitutional alterations.

These observations support the hypothesis that constitutional alterations of the ATM gene may contribute to the pathogenesis of some early-onset sporadic breast cancer.

Notably, these tumors also represent the sole manifestation of a heritable cancer predisposition syndrome caused by constitutional alterations of SMARCB1/INI1 tumor suppressor gene [ 5, 6].

To assess the CDH1 germline mutation frequency in low- and high-risk areas for GC, we reviewed all E-cadherin constitutional alterations identified from 1998 to date, considering the worldwide geographic distribution.

To investigate this possibility we have analysed an unselected series of WT cases, for the presence of somatic and constitutional alterations to GPC3 in tumour and normal tissue respectively.

The reported CDH1 constitutional alterations are defined as truncating, deletion, insertion, splice site, non-sense, and missense mutations (Table 1); we grouped these mutations as non-missense (truncating, deletion, insertion, splice site and non sense) or missense mutations.

CDH1 germline mutations are associated with the development of the autosomal cancer syndrome namely Hereditary Diffuse Gastric Cancer (HDGC) [ 1, 2]; about 25-30% of families fulfilling the clinical criteria for HDGC established by the International Gastric Cancer Linkage Consortium (IGCLC) have constitutional alterations of the CDH1 gene [ 3].

CDH1 germline mutations are associated with the development of autosomal cancer syndrome, namely hereditary diffuse gastric cancer (HDGC); about 25 30 % of families fulfilling the clinical criteria for HDGC established by the International Gastric Cancer Linkage Consortium (IGCLC) have constitutional alterations of the CDH1 gene [ 7].

Constitutional change requires bipartisanship.