The sampling process was implemented in two steps: constitution of the sampling frame preceded actual sampling of subjects.
The constitution of the full eligible sample is planned during the last trimester of 2010, and the inclusion of cohort participants will start at the beginning of 2011.
The constitution of the full eligible sample is planned during the last trimester of 2010, and the cohort will be launched at the beginning of 2011.
After plotting each component of the chemical constitution of the studied groundwater samples, the main group can be distinguished into Na + K > Mg > Ca and Cl > SO4 > HCO3, which reflects an advanced stage of hydrochemical evolution (Fig. 7b).
It remains unknown whether searching in foreign language journals would have altered the constitution of our sample or results.
It remains unknown whether searching in other language journals would have altered the constitution of our sample or results.
The PHASE software version 2.1 [ 64, 65] was used to determinate the most probable haplotype constitution of each sample.
Genotypes were identified using FinchTV software v.1.4.0 and the most probable haplotype constitution of each sample was determined by PHASE software v.2.1.
The constitution of representative samples of farms with well known infection status was possible for several reasons: first, the epidemiological situation of CA in France is well surveyed [ 3], second, a large number of farms and animals had been monitored for many years as part of several distinct eradication campaigns and third, animals had not been vaccinated against this agent.
Raman spectra allow assessment of the overall molecular constitution of biological samples, based on specific signals from proteins, nucleic acids, lipids, carbohydrates, and inorganic crystals.
This discrepancy in the constitution of samples cannot be controlled and could induce bias.
