Although the cause of lethality of TANK1−/−TANK2−/− or TANK1+/−TANK2−/− embryos is not fully defined, the lack of umbilical cord and failure of placental development may constitute the cause of failed embryonic development.
However, we cannot conclude yet whether this regulation constitutes the cause, by retarding plasmodia growth in host cells, or the result of partial clubroot resistance.
But this distinction does not affect the principle, since the contribution of background exposures, if they constitute the cause of the background to be added to, must be through effects on the same distribution of the internal physiological variable.
Sepsis, a systemic inflammatory response to infection, annually kills more than 210,000 people in the United States [ 1] and is one of the most challenging clinical problems worldwide, constituting the leading cause of death in non-coronary intensive care units [ 2].
These things which are wholly other and wholly foreign to anything we experience constitute the Unknowable cause or causes of the phenomena of which we are ordinarily aware.
Distribution of causes of mortality was similar for men and women, with the exception of external causes, which constituted the second cause of death among men and did not figure among causes of death for women.
In industrialized countries, stroke constitutes the leading cause of adult handicap, the second leading cause of dementia, and the third leading cause of death [ 1].
Chronic glomerulonephritis, usually caused by primary glomerular disease, constituted the leading cause of end-stage renal failure (ESRD) in China, followed by diabetic and hypertensive nephropathies [3].
Adhesions are the most common cause of bowel obstruction after surgery, and they constitute the leading cause of long-term reoperation following abdominal and pelvic surgery.
Non-communicable diseases constitute the leading cause of death in the country and the leading cause of hospitalization in government hospitals throughout the country 3.
