In fact, its use increased so significantly, the payments for ADT constituted the second highest expense for Medicare part B expenditure in 2003. 1 The realization of this magnitude led to careful scrutiny of the risks and benefits of therapy as well as the restructuring of reimbursement for ADT by Medicare.
If, instead, we consider the highest total CO2 release (vents + diffuse) of 3,420 t d−1, measured in January 2015, this would constitute the eighth highest value ever measured at volcanic plumes.
According to 2006 FBI statistics, hate crimes based on sexual orientation constituted the third highest category reported and made up 15.5percentt of all reported hate crimes.
Correspondingly, its nonmedical prescription opioid use and prescription opioid related harms were high, and may now constitute the third highest level of substance use burden of disease [ 3].
From the systems biology perspective, IDA was ground-breaking, because Maathuis et al. (2010) succeeded in predicting expression changes of 5361 genes in 234 yeast deletion strains from 63 expression profiles of wild type yeast, thus constituting the first high throughput analysis of virtual perturbation experiments.
The karstic Lake Montcortès sedimentary sequence spanning the last 1548 yr constitutes the first continuous, high-resolution, multi-proxy varved record in northern Spain.
The dataset constitutes the first systematic measurements on the Higher Himalayan Crystalline rocks.
This constitutes the first published observation of such high β,β′ selectivity and 2,6-/2,7- ratin in the liquid phase alkylation of naphthalene.
The personal and societal impacts of dementia are considerable [ 6- 8], and it constitutes the third most common neuropsychiatric disorder in high income countries [ 9].
