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This constitutes the first reported example of cationic hydrogels in which the length of segments between cross-links is kept constant.
The structure of the corresponding complex was solved at a resolution of 2.5 Å using molecular replacement and constitutes the first reported structure of a human ephrin receptor bound to an antibody.
In particular, the expression dataset in ExprTargetDB constitutes the first reported study of miRNA-mediated gene regulation using the HapMap samples [6], [7] that have been so important in transcriptome-based studies of complex traits [34] and pharmacologic phenotypes [17].
This verifies the validity of the synthetic strategy employed and constitutes the first reported application of Nimzyme to a non-carbohydrate-active enzyme.
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Specific cases are illustrative and novel, constituting the first reported examples of these techniques to our knowledge.
The route followed herein to prepare a folic-acid based radiotracer constitutes the first report of radiolabeling folic acid using the [99mTcN PNP ]2+ as a radiosynthon.
This study constitutes the first report of completely sequenced IncP-1ε plasmids from water environments, and enhances our understanding of the geographic distribution and genetic diversity of these replicons.
To our knowledge, the purple colour change observation in the Yl-mch1 engineered in this study constitutes the first report of such an effect of displayed mCherry on both solid and liquid medium.
This study constitutes the first report of a PTP-targeted strategy able to selectively open the PTP and consecutively provoke cell death in some cells whilst sparing others.
This constitutes the first report of elevated chemotherapy-induced senescence via functional inactivation of HIF-1α in an established human cancer cell line.
To our knowledge, this constitutes the first report concerning mtDNA somatic mutations in cancer and normal hematopoietic cells that systematically (re)analyzed samples that were previously the target of analysis in a laboratory.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com