Sentence examples for constitutes a target of from inspiring English sources

Hepatitis C virus (HCV) RNA-dependent RNA polymerase NS5B constitutes a target of choice for the development of anti-HCV drugs.

Because of its physiological role, the β2-adrenergic receptor constitutes a target of interest for a wide range of drugs[2].

Interesting in this context is that RACK1, located at peripheral initial adhesion structures, has been shown to bind to focal adhesion kinase [44], which constitutes a target of the antiphagocytic effector YopH [55].

In particular the soluble isoform GAD67 is present mainly in the cytoplasm [34] and, therefore, may constitute a target of the UPS.

Asked if the revelations constituted a targeting of Italians, Mr. Giuliani replied, "People have to draw their own conclusions".

The considerable modification of patterns in the moderately disabled group might indicate that such groups constitute a target for provision of services, in cases where severe/extreme disability can be reduced by personal or technical aid.

In contrast to the normal kidney, which could constitute a target for adverse actions of COX-2 inhibitors, recent experimental studies showed increased renal COX-2 expression in several models of renal injury, such as the remnant kidney, renovascular hypertension, and diabetes, and implicated COX-2 in the progression of renal failure.

Vascular endothelial cells constitute a target for blood-borne executors of the immune system, antibodies and T cells, and several experimental models suggest that vascular endothelial cells are targets for alloreactive T cells in acute and chronic GVHD.

Founders also expressed surprise at the fact that Jordan has 24/7 electricity--a basic piece of knowledge they should all have, since Jordan constitutes a target or test market for most of them.

This challenge though does not constitute a target, nor is it evidence of one".

Given that RIPK1, RIPK3 and MLKL interact upon necroptosis induction, we set out to assess which of them constitutes a direct target of ponatinib.