Sentence examples for constitutes a significant problem from inspiring English sources

This constitutes a significant problem for designers, developers, building materials producers and local authorities responsible for the spatial policy.

This might change from medium to long term due to technological developments, but it constitutes a significant problem for many local communities.

The photocytoxicity associated with TMR-TAT constitutes a significant problem when one considers using this peptide in the context of photo-induced delivery of macromolecules into live cells.

Easy availability, access to re-fills without prescription and self prescription compounded with the lack of understanding of abuse potential of benzodiazepines constitutes a significant problem demanding serious consideration from health policy makers.

Therefore, against the backdrop of the obesity epidemic, IGT constitutes a significant problem in youth, especially those from ethnic minority populations and those with a family history of type 2 diabetes.

Smoking among young people constitutes a significant problem that is destined to worsen in the absence of any comprehensive efforts focused on strict anti-smoking legislation, policies and tobacco control interventions targeting children at a young age.

Post-TKA functional limitations constitute a significant problem.

Musculoskeletal pains constitute a significant problem of the contemporary society [ 1].

Adverse events (AEs) in hospitals constitute a significant problem with serious consequences and a challenge for public health.

Falls and fall-related injuries in the elderly constitute a significant problem for individuals as well as for society.

These effects are similar to the tumour lysis or surgical crush syndromes and should not constitute a significant problem in clinical practice, where the tumour mass to total body mass ratio will normally be much smaller.