Sentence examples for constitutes a significant challenge from inspiring English sources

Uncontrolled hypertension constitutes a significant challenge throughout the world.

Uncertainty propagation analysis in engineering systems constitutes a significant challenge.

Uncertainty propagation in complex engineering systems with fuzzy variables constitutes a significant challenge.

The robust identification of nonlinear frictional dynamics constitutes a significant challenge for the model based friction compensation in advanced control of electro-mechanical drives.

Living with a long-term condition such as sickle cell disease during adolescence constitutes a significant challenge for the key stakeholders due to the combined effects of chronic illness and adolescent development.

Treatment of relapsed/refractory infant ALL constitutes a significant challenge as there is no defined therapy.

Variants of unknown significance in the CAPN3 gene constitute a significant challenge for genetic counselling.

Highly flexible proteins constitute a significant challenge in molecular docking within the field of drug design.

These momentous events constitute a significant challenge to the legitimacy of the Iranian regime and the future of the Islamic Republic.

The corresponding highly nonlinear and rapidly time-varying dynamics constitute a significant challenge for the autopilot design.

Since weights can no longer be stored in read-only memories, these dynamic weights constitute a significant challenge for digital circuits, in addition to the usual issues of area occupation, fixed-point arithmetic and nonlinear functions computations.