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Timeliness of guidelines updates also constitutes a serious issue [8] and it can affect the reliability of these documents, especially for fields where evidence changes rapidly.
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Hepatitis B virus infection is a common viral disease, which constitutes a serious health issue throughout the world due to its morbidity, mortality and economical losses.
The burden of oral diseases is high among underprivileged people in North America and constitutes a serious public health issue [ 1, 2].
College Board rep Sandra Riley noted that the material that Reuters received constitutes "a serious criminal matter".
As a result, the report concluded, migration also constitutes a serious brain drain for Afghanistan.
When it does occur, it constitutes a serious criminal offense".
"This constitutes a serious breach of copyright violation and theft of Warner Bros property.
Any more than four people waiting at the bottom constitutes a serious queue.
Olive mill wastewater constitutes a serious environmental problem.
However, it constitutes a serious safety problem for buildings.
Malnutrition constitutes a serious problem of public health.
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