Sentence examples for constitutes a key step from inspiring English sources

The binding of the V3 loop to CXCR4 or CCR5 determines the cell tropism of HIV-1 and constitutes a key step before HIV-1 cell entry.

In conclusion, the sequence of the patulin cluster in P. expansum constitutes a key step for a better understanding of the mechanisms leading to patulin production in this fungus.

Elucidation of the structural basis directing AS metal interactions and their effect on AS aggregation constitutes a key step towards understanding the role of metal ions in AS amyloid formation and neurodegeneration.

The judge's OK constitutes a key step in lifting the carrier out of its second bankruptcy.

The design of QSAR/QSPR models is a challenging problem, where the selection of the most relevant descriptors constitutes a key step of the process.

The loss of mitochondrial integrity as a consequence of apoptogenic complexes formed on the outer membrane constitutes a key step in controlling progression of apoptotic cascades.

The results of this study constitute a key step towards improving space weather modelling and prediction.

Thus, identifying genetic factors that regulate oil accumulation in algae will constitute a key step toward understanding and manipulating oil content in algal cells.

Moreover, we also demonstrate that c-jun N-terminal kinase (JNK) activation constituted a key step for the expression of both NOX-4 and fibrotic markers putting the TGF-β-dependent activation of this route as an initial event during the breast stromal myofibroblasts differentiation process.

In phase 1 of the biosynthesis of artemisinin, HMGR [ 18] catalyzes the first transformation in the mevalonate pathway, which is irreversible under physiological conditions, and thereby constitutes a key committed step in the biosynthesis of sesquiterpenes (as well as triterpenes) in the cytosol of higher plants.

Endogeneity constitutes a key concern in the relationship between external sanctions and audit quality.