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Also this cluster has been implicated in metabolic oscillations and constitutes a key regulator of the biosynthetic program peaking in the oxidative phase [ 21].
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More specifically, it has been shown that CYLD constitutes a key negative regulator of NF-κB and JNK in macrophages from Cyld null mice that have been treated with CD40 or ligands against TLR4 and TLR2 [4].
The Youth Movement constitutes a key political constituency that may eventually form a distinct party.
Its prevention therefore constitutes a key goal of management.
Avoidance of phago-lysosome fusion within the macrophage constitutes a key survival mechanism of TB.
However, the generation of realistic complex disease models constitutes a key challenge.
Computational signal detection constitutes a key element of postmarketing drug monitoring and surveillance.
This probably constitutes a key mechanism for opioid-induced depotentiation [ 36].
Thus, nitrate signaling constitutes a key point of plant adaptation to environment.
OPN is a key regulator of bone biology and appears, based on our studies, to also be a key regulator of adipocyte biology.
Interesting recent findings in pancreatic cancer suggest miR-101 as a key regulator of stem cell protein markers; its loss favoring the stem cell phenotype and its re-expression constituting a possible therapeutic strategy [ 29].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com