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Depending on which expert you ask, though, there are a variety of answers as to what actually constitutes a flaw.
To equate such low-intensity microglial activation in human brain with artificially produced high-intensity microglial neurotoxicity in vitro constitutes a flaw in scientific reasoning explained possibly by immature judgment or premature ambition.
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American officials and the head of the International Atomic Energy Agency, Mohamed ElBaradei, have said that the treaty provision allowing countries to renounce it, with just 90 days' notice, constitutes a major flaw in the effort to keep nations from becoming nuclear powers.
Moreover, no measurable, verifiable elimination and limit on its uranium stockpile constitutes a fatal flaw in any agreement.
On an issue that is this critical to public safety and the overall success of the sex offender treatment program, this failure of adequate vetting and thorough debate constitutes a fatal flaw with the bill.
However, this does not bring us closer to deciphering or articulating what constitutes a 'fatal flaw'.
Yet they constitute a noticeable flaw indeed, given the book's economical — even parsimonious — structure.
Indeed, Schmidt et al. [1] state this in the first sentence of their discussion: '...it would not be expected that a predacious coleopteran nontarget species exhibits susceptibility to the lepidopteran-active protein Cry1Ab.' However, the lack of an explaining mechanism for a documented phenomenon certainly does not constitute a 'methodological flaw' (see below).
In both the earliest materials and Geoffrey he is a great and ferocious warrior, who laughs as he personally slaughters witches and giants and takes a leading role in all military campaigns, whereas in the continental romances he becomes the roi fainéant, the "do-nothing king", whose "inactivity and acquiescence constituted a central flaw in his otherwise ideal society".
In the food markets and home environments, a flaw in the cold chain constitutes a risk factor for the growth and dissemination of Listeria [ 3, 34].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com