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Efficient clearance of damaged mitochondria by autophagy, termed mitophagy, constitutes a critical component of MQC.
The application was developed as a modular extension of our previous work and constitutes a critical component within our long-term effort of advancing a data processing pipeline for S-system estimation from metabolomic time series [ 13, 22].
On the basis of the prevalence of alternative splicing events in the plant circadian clock genes in the literature [ 20, 26, 27, 34, 35], we anticipated that alternative splicing of the core clock genes constitutes a critical component of the clock function.
Recently, we suggested that, similar to PPIF, the c subunit of the FO ATP synthase constitutes a critical component of the mPTP and that it is required for the MPT, mitochondrial fragmentation and cell death induced by oxidative stress or mitochondrial Ca2+ overload [37].
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Boiler turbine units constitute a critical component of a co-generation system.
Physical activity (PA) interventions constitute a critical component of cardiovascular disease (CVD) risk reduction programs.
It is clear that a study of the glass recipes of the suppliers of beads will constitute a critical component of future investigations of beads traded into Africa after the sixteenth century AD.
Although sensory neurons constitute a critical component for the proper function of the nervous system, the in vitro differentiation of functional sensory neurons from human stem cells has not yet been reported.
These results suggest that functionally intact phagocytes constitute a critical component of the host defense against these Gram-positive bacteria.
Thus, along with SLP76, Grb2, and Syk, Vav proteins constitute a critical component of the ITAM signalosome [23], [24], [25].
Moreover, these findings have important implications in understanding the use of IL-7 and IL-15 as adjuvant for therapeutic vaccination regimen against intracellular pathogens where CD8+ T cells constitute a critical component of protective immunity.
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