CVID constitutes a complex syndrome with various clinical phenotypes, making it difficult to define pathogenesis and find precise genetic defects.
Angiogenesis is necessary for cancer progression and constitutes a complex process with many different cooperating pathways, where VEGF-A, NO and TGF-β seem to have an important role.
HDX MS was used to study p110α and showed that p110α in complex with a regulatory subunit (p85α) constitutes a complex catalytic cycle characterized by distinct conformational steps.
The metabolic syndrome (MetS) constitutes a complex disorder combining obesity, dyslipidemia, hyperglycemia, and hypertension, associated with an increased risk of cardiovascular diseases, especially CAD.
These activities involve the mastery of the many sub-activities that constitute a complex activity with goals that challenge abilities of the agent.
The basiconic, trichoid and coeloconic sensilla constitute a complex reception system, with each type of sensilla presenting its own characteristics according to its structure, the type of olfactory receptors expressed in its ORNs and the odorant type that it is able to detect.
According to Jefferies and colleagues, prefrontal cortex, together with temporo-parietal attentional areas, may constitute a complex cognitive control network with an important role in tasks with high level of selection demands, the higher the competition, the higher the demands, the more critical the role of selection mechanisms [see also Peers et al. (2005)].
(Pt 6) Interplay between several individual, social and structural determinants emerged, constituting a complex interaction that interfered with the experience of living with pain.
