In fact, in spite of the efforts that have drastically reduced the occurrence of aluminium dialysis diseases, they so far constitute a cause of great medical concern.
Does the complaint herein state facts sufficient to constitute a cause of action?
Much more can be said about the RCM, but what must be discussed is Holland's notion of what constitutes a cause, as his views are central to the arguments made in this paper.
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by chronic inflammatory synovitis, leading to invasion of synovial tissue into the adjacent cartilage matrix with degradation of articular cartilage and bone, which constitutes a major cause of progressive disability and crippling of RA patients [ 1].
Therefore, recurrent or sustained elevation of circulating ET-1 constitutes a plausible cause of some acute and chronic adverse health effects of air pollutants (Thomson et al. 2005).
Together, this group of disorders constitutes a major cause of young-onset dementia.
Stroke constitutes a major cause of acquired disability in adults and the second most frequent cause of mortality in developed nations [2].
Visual impairment also negatively affects the Health-Related Quality of Life (HRQoL) of patients [ 9, 10], and constitutes a major cause of disability that affects individuals, family and society, and is associated with an increased risk of institutionalisation and death [ 1, 11- 13].
It is imperative that we further explore our understanding of AECOPD as this clinical diagnosis constitutes a major cause of morbidity and mortality in the COPD population, with a 50% mortality at 3.6 years, a 75% mortality at 7.7 years, and a 96% mortality at 17 years following the index hospitalization for AECOPD [ 3].
Critical illness polyneuromyopathy (CIPM) constitutes a significant cause of difficulty in weaning patients from the ventilator, prolongation of their stay in the ICU and increased morbidity and mortality.
