Sentence examples for constitute the rationale from inspiring English sources

The present study may constitute the rationale for the design of a randomized controlled study to address the effect of such a combined organ-support strategy on mortality.

These purposes are recognized by the expert members of the parent discourse community and thereby constitute the rationale for the genre" (Swales, 1990, p. 58).

The role of enteric flora in the pathogenesis of inflammatory bowel disease constitutes the rationale for the use of antibiotics as adjuvant agents in the treatment of ulcerative colitis (UC) and Crohn's disease.

Demonstration of HER-2 antigen overexpression in breast cancer constitutes the rationale for treatment with Trastuzumab (Baselga et al, 1998).

The literature and the knowledge of the long-term effects of PBL on self-care after CHD have not been scrutinised or rigorously evaluated, and this constituted the rationale for designing a randomised study.

Both factors (genetic polymorphisms and intestinal microflora) can influence irinotecan intestinal toxicity: this constitutes the rationale for the necessity of evaluating also intestinal microflora and β-glucuronidase role in future studies investigating its interindividual variability.

The proven synergistic activity of paclitaxel with anthracyclines (Gianni et al, 1995), and the single-agent activity of this agent as well as the demonstrated equivalent activity of PLD to doxorubicin in advanced STS, constituted the rationale for the present study performed by the Hellenic Cooperative Oncology Group.

Improving semantic interoperability by a structured representation of clinical procedures, findings and diseases constitutes the main rationale for the development of clinical terminologies and classification systems.

Recruitment of poorly ventilated alveoli, unloading of respiratory muscles, favorable hemodynamic impact on coexisting decompensated acute heart failure, constitute the potential patho-physiological rationale for the use of mechanical ventilation during ARF in these patients.

The rationales underlying our decisions are that the smoking-related phenotypes are highly inter-related, the male smokers constitute the predominant fraction of all smokers in the total sample, and the three genetic models cannot be treated as totally independent.

Tinkerbirds constitute the genus Pogoniulus.