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Since wbmF, wbmG, and wbmH together constitute the pathway for converting UDP-ManNAc3NAcA to the UDP-GalNAc3NAcA for the O PS backbone [ 25], they also appear to be conserved as one segment.
The inferred HTCS_Hep regulon includes genes for enzymes and transporters that together constitute the pathway for utilization of heparin or heparan sulfate to N-acetylglucosamine, whereas BT4675 encodes the periplasmic heparin lyase I/heparinase I (HepC).
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In T lymphocytes, store-operated Ca(2+ -release-activated Ca(2+ -release-activatedonstitute the sole pathway for Ca(2+ -release-activatedntigen-reCaptor engagement, and their function is essential for driving the program of gene expression that underlies T-cell activation by antigen.
These three enzymes constitute the canonical pathway for triglyceride breakdown [20 23].
Clathrin-mediated endocytosis, however, may not constitute the sole pathway for synaptic vesicle endocytosis.
The Rorα/Lhx1 double positive dLGN neurons constitute the thalamocortical pathway for conveying visual information to the brain (Chou et al., 2013).
In plants, Dhonukshe et al. (2007) have showed that clathrin-dependent endocytosis constitutes the predominant pathway for constitutive internalization of PM proteins.
As mentioned above, mutagenesis in mucA constitutes the main pathway for conversion to mucoidy, although other possible pathways that convergently lead to alginate overproduction have also been described [14], [15], [17].
While several different pathways have been proposed to mediate Okazaki fragment maturation in eukaryotic systems, the central role of these three enzymes in S. solfataricus appears to correlate with their orthologues constituting the core pathway for maturation in eukaryotes (Ayyagari et al, 2003).
Together with GAD67, these enzymes constitute the major biosynthetic pathway for GABA in the central nervous system (Soghomonian and Martin, 1998).
Genes for aging (named gerogenes [ 37]) constitute the TOR pathway [ 37].
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