Both these processes constitute significant engines of change.
But scientists say there was debate in their ranks over what might constitute "significant chemical change".
Nevertheless, the developments just reviewed constitute significant changes.
Achieving that would constitute significant progress and make the massive loss of life less senseless.
Administrative datasets constitute a significant information resource for government and are used to manage, monitor, assess and review a range of service areas.
The Arkansas spill, while smaller, "constitutes significant new circumstances and information that is relevant to environmental concerns and the potential impacts of Keystone XL," they wrote.
Even with an interface available, the dynamics of the wireless channel and the variability in the number of users attached to a cell, users' location, and interference conditions, this coordination constitutes a significant information overhead resulting in large delays.
Despite this progress, there are also large areas from which little information is available, thus constituting significant paleo-geographic gaps in the last interglacial record.
Debate itself constitutes significant change.
There are also disagreements over what constitutes "significant" impact.
