Sentence examples for constitute a significant challenge from inspiring English sources

Variants of unknown significance in the CAPN3 gene constitute a significant challenge for genetic counselling.

Highly flexible proteins constitute a significant challenge in molecular docking within the field of drug design.

The corresponding highly nonlinear and rapidly time-varying dynamics constitute a significant challenge for the autopilot design.

Since weights can no longer be stored in read-only memories, these dynamic weights constitute a significant challenge for digital circuits, in addition to the usual issues of area occupation, fixed-point arithmetic and nonlinear functions computations.

Such unavoidable costs constitute a significant challenge to prey animals attempting to cope with the predatory environment, so the prey species might be expected to evolve some secondary means of dealing with these costs.

These demographic changes will constitute a significant challenge for the health care systems involved, particularly nursing homes.

Uncertainty propagation analysis in engineering systems constitutes a significant challenge.

Uncontrolled hypertension constitutes a significant challenge throughout the world.

Uncertainty propagation in complex engineering systems with fuzzy variables constitutes a significant challenge.

The robust identification of nonlinear frictional dynamics constitutes a significant challenge for the model based friction compensation in advanced control of electro-mechanical drives.

Living with a long-term condition such as sickle cell disease during adolescence constitutes a significant challenge for the key stakeholders due to the combined effects of chronic illness and adolescent development.