Sentence examples for constitute a profound from inspiring English sources

Moreover, we think that pushing someone to the brink of suicide, particularly where the person comes from a culture with strong taboos against suicide and it is evidenced by acts of self-mutilation, would be a sufficient disruption of the personality to constitute a "profound disruption".

The area's natural resources -- the Great Lakes contain one-fifth of the world's supply of fresh water -- constitute a profound competitive advantage against drought stricken economies in the Inland West, the southern Great Plains and parts of the Southeast.

Thus, as we discuss later in this section, the extraordinary disparities in life expectancy, child survival and health that distinguish those who live in rich and poor countries constitute a profound injustice that it is the duty of the global community to redress.

His species, His oceans, His climate, the delicate balance that nourishes all the living systems of our Mother Earth constitute a profound scripture written directly without human intervention.

These missing cases constitute a profound stain on the court's record, and they are worth recalling on this week's tenth anniversary of John Roberts's swearing-in as Chief Justice.

In short, we've been looking for signs of the future in verse of the past (in part because certain scions of the past have willed it so) rather than allowing that the next authentic avant-garde will, while acknowledging its heritage in ways large and small, nevertheless constitute a profound and shocking break from any avant-garde that preceded it.

Arguably the most important addition to the Constitution other than the Bill of Rights, the amendment constituted a profound change in federal-state relations.

This constitutes a profound invasion of children's online privacy, and significantly restricts the potential of the Internet to play a constructive role in children's lives.

Also, the European diesel car boom constitutes a profound technology change.

Transfusion of allogeneic blood components from heterologous donors constitutes a profound immunologic stimulus to the recipient, in addition to being a potential route of transmission of lymphotropic viral infections.

As literary scholar Kari Lokke writes, The Last Man, more so than Frankenstein, "in its refusal to place humanity at the center of the universe, its questioning of our privileged position in relation to nature ... constitutes a profound and prophetic challenge to Western humanism".