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Electron microscopy confirmed that neurons in core region at 3 h were not healthy, since cytosolic (cyt) and mitochondrial structures (M, and insets in Figure 7C) disintegrated, compared to those in intact neurons (Figure 7C), which constitute a marker of dying cells [47] [49].
Thereby, this strongly suggests that activation of the cytoplasmic signalling pathway could constitute a marker of tumour aggressiveness.
Syndecan-1, E-cadherin and c-met constitute a marker signature associated with angiogenic and lymphangiogenic factors in DCIS.
Interestingly, an absence of BP reactivity seems to constitute a marker of brain death within 1 week (specificity 100%%).
Derived from cell membrane shedding as a result of activation or apoptosis, circulating MPs constitute a marker of vascular and systemic disease [ 7].
Conclusion: Our results support a role of survivin in colorectal carcinogenesis while the −31G/C snp may constitute a marker of survival.
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A high Pcv aCO2 might identify patients who remain inadequately resuscitated and constitutes a marker of global perfusion that could aid in identifying a hypoperfusion-related hyperlactatemia [12, 13].
pp72-IE1 is expressed with immediate early kinetics upon infection and is not part of the HCMV particle and therefore constitutes a marker for successful HCMV entry and initiation of gene expression.
Thus, HP1α constitutes a marker of prognostic value, in breast cancer and potentially in other types of cancer.
Flagellar sequence variation constitutes a marker with widespread potential uses for studies of population genetics and phylogeny of bacterial species.
For this purpose, western blot analysis using a phosphospecific Ab directed against Src-Tyr416, which constitutes a marker of Src activation, was performed.
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