"constitute a major risk" is a grammatically correct and commonly used phrase in written English.
It means that something or someone poses a significant danger or threat. Example: The use of pesticides in farming practices can constitute a major risk to the environment and public health.
Landslides induced by high-intensity or prolonged rainfalls constitute a major risk factor in Nigeria especially because they have generally been poorly defined in the past.
29 Rather, figure 2b indicates that smallpox ceased to constitute a major risk to adults.
Men who have sex with men (MSM) constitute a major risk group for HIV transmission.
Mood disorders are, at the same time, known to constitute a major risk factor for decreased sexual function [ 3].
Serum A-FABP levels constitute a major risk factor in the development of central arterial stiffness in the geriatric population.
Thus, available data indicate that germline E-cadherin mutations do not constitute a major risk factor for breast cancer.
It was noted that even amongst the few users of dual methods, only a mere 26.8% practiced it as a form of safer sex consistently, while majority were inconsistent in its use, this constitutes a major risk factor for STIs/HIV and unplanned pregnancy and may explains the high prevalence of STIs and unplanned pregnancy noted among respondents who were non users or inconsistent users.
The high EBV DNA load constitutes a major risk for the development of EBV-related lymphoproliferations.
Inadequate drinking water quality constitutes a major risk factor for cholera and other diarrheal diseases around the globe, especially for young children in developing countries.
Sexual interest toward prepubescents and pubescents (pedophilia and hebephilia) constitutes a major risk factor for child sexual abuse (CSA) and viewing of child abusive images, i.e., child pornography offenses (CPO).
Cigarette smoking is the worldwide leading cause of preventable morbidity and mortality and constitutes a major risk factor for atherosclerotic vascular disease, including stroke and coronary artery disease [9].
