Long duration super-pressure balloons constitute a great challenge in scientific ballooning.
Cardiac arrhythmias constitute a great challenge in the ICU, since they aggravate a borderline cardiopulmonary function.
However, in areas where there are one or two service providers and the tendered contracts constitute a large proportion of the total market, there are challenges.
Efficient and effective delivery of poorly water-soluble drug molecules, which constitute a large part of commercially available drugs, is a major challenge in the field of drug delivery.
Philosophical works constitute a large percentage of the total compilation.
Besides, hitchhikers constitute a large international community.
GPCRs constitute a large superfamily of integral membrane protein receptors.
PPR genes constitute a large multigene family in higher plants.
Bacteria (; singular: bacterium) constitute a large domain of prokaryotic microorganisms.
Flammable methane is another such asphyxiant, and can constitute a large percentage of your fart gas.
