The high prevalence of multimorbidity constitutes a high burden for the patients and a challenge for primary care physicians simultaneously.
Moreover, it is characterised by a high health care utilisation constituting a high burden of disease, mainly due to hospital admissions [ 1].
Human immunodeficiency virus (HIV) and tuberculosis (TB) co-infection constitutes a high-burden disease in Thailand, where 12,890 individuals died from TB in 2009 and where HIV accounts for 17% of TB cases, the highest figure in the south-east Asian region. 1 Early case identification followed by adequate treatment is the cornerstone of TB control programs.
Altogether, the findings suggest that undiagnosed ADHD, especially in combination with antisocial behaviour and poor cognitive functions, constitute a high risk for the development of an extensive clinical burden, which, in turn, is associated with high risks, such as accidents, drug overdoses, and mortality, as well as family burdens and high care costs for society [ 50- 52].
Pediatric patients constitute a high risk population.
It can have a substantial impact on the health-related quality of life and constitutes a high socioeconomic burden on the health care system [ 2, 3].
That's a high burden of proof.
They impose a high burden on under-funded health services.
Traits with a high burden evolve very slowly.
Setting: The Philippines, a high burden country for tuberculosis (TB).
