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Endothelial dysfunction and impaired angiogenesis constitute a hallmark of hypercholesterolemia.
PMNs are the first line of defense in the innate immune response to bacterial infection, and their activated phenotype may constitute a hallmark of infection [5].
Metabolic alterations constitute a hallmark in cancer cells: They are required for driving transformation, progression and spreading cancer in tissues [16].
Catalytic activity and binding categories thus constitute a hallmark of the venom gland transcriptomes analysed to date.
PMNs are the first line of defense in the innate immune response to bacterial infection, and their activated phenotype may constitute a hallmark of infection [ 5].
Our work thus suggests that detection of sMIC molecule in maternal plasma may constitute a hallmark of altered maternal immune functions that contributes to vascular disorders that complicate pregnancy, notably by impairing NK-cell mediated production of IFN- γ, an essential cytokine favoring vascular modeling.
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The abnormal or lack of P-cad expression could constitute an hallmark of aggressive biological behavior in OSCC Invasive OSCC, in spite of improved therapeutic procedures, actually show a generally poor prognosis since its local aggressiveness and metastases.
Loss of normal tight junction functions constitutes a hallmark of human carcinomas.
A telling example is that of the redox imbalance that constitutes a hallmark of CF. Local and systemic accumulation of oxidants are believed to impact CF blood neutrophils, which display lower intracellular GSH levels [69].
Henipavirus PNT and NTAIL were found to be highly sensitive to proteolysis, a property that constitutes a hallmark of structural disorder (see [47] and references therein cited).
Thus, scanning human tumors with positron emission tomography (PET) [17] has verified that a high uptake rate of glucose constitutes a hallmark in cancer cells, presumably required to confer adaptive advantages when facing acidic and hypoxic environments [19].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com