Sentence examples for constitute a functional from inspiring English sources

Mutational analysis shows that although one of these sequences is required for Atg36 function, it is not conserved and does not constitute a functional AIM (Supplementary Figure S5).

These parts of the brain constitute a functional "default network" 30 needed for theory of mind processing and executive function, and these parts appear to be critically differently functioning in autism.

The semantic umbrella term nanotechnology covers every branch of science pursuing controlled manipulation of matter at the nanoscale, at which point a discrete set of atoms constitute a functional object.

With the identification of three major P-TEFb complexes that constitute a functional network to control HIV and cellular gene expression, we are in a unique position to investigate whether and how this network may be therapeutically exploited to treat human diseases such as HIV/AIDS and cancer.

Two adjacent vertebrae, the intervertebral disc, spinal ligaments and facet joints between them constitute a functional spinal unit [2] (Fig. 1).

Altogether we conclude that NLS1 constitute a functional, necessary and sufficient nuclear signal.

Nevertheless, in vitro reconstitution of mammalian eIF3 have implicated three conserved subunits (eIF3a, eIF3b, eIF3c) and three non-conserved subunits (eIF3e, eIF3f and eIF3h) as being required for eIF3 function, and constituting a functional mammalian eIF3 core, whilst indicating that the two conserved subunits eIF3g and eIF3i might be dispensable [ 7].

Association of nuclear factor-κB with a specific inhibitory protein (IκB), which masks its nuclear localization signal, constitutes a functional system in which DNA binding/activation and regulatory/inhibitory functions are performed by two separate proteins that can interact [ 23].

At a more fundamental level, there is no consensus on which model would work best in a given situation and what constitutes a "functional" market.

It seems, therefore, that in these compounds the R substituent constitutes a functional probe in the dynamic agonist antagonist conformational equilibrium.

These are a first protein fused to a DNA-binding domain of known specificity (hybrid 1); a second protein fused to a transcriptional activation domain (hybrid 2), that can interact with the first protein, constituting a functional, albeit composite, transcription factor; and one or more reporter genes transcribed based on the binding of the composite transcription factor.