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We believed our patient had a constellation consistent with Gitelman's syndrome.
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This constellation is consistent with a urinary acidification defect in the distal nephron ('classical' renal tubular acidosis type I).
DOI: http://dx.doi.org/10.7554/eLife.01913.006 Analysis of peripheral blood from TSC-KO mice revealed a constellation of changes consistent with macrocytic anemia.
Although the exact mechanism is unknown, the time course and constellation of symptoms are consistent with a possible inflammatory pathophysiologic condition.
A total of 106 cases reported term (s) consistent with constellation of hypersensitivity reactions.
For final assessment, the case reports with terms consistent with constellation of hypersensitivity reactions and critical terms were included.
Only 106 case reports specified andrographis herbal product as the only suspected drug and reported at least one term consistent with constellation of hypersensitivity reactions.
To be specific in final analysis, we investigated in details only those reports with terms consistent with constellation of hypersensitivity reactions [ 16] and considered critical terms according to WHO criteria [ 17].
Case reports were included for final analysis if they met the inclusion criteria; 1) reports with andrographis being the only suspected cause, 2) reports with terms consistent with the constellation of hypersensitivity reactions, and 3) reports with terms considered critical terms according to WHO criteria.
Thus, the higher than average codon usage bias observed for the gene constellations 5PP and EE is consistent with results of an earlier study that reported high codon usage bias in regions of high gene density [ 3].
The latter constellation was present in our cohort, consistent with both a leaky and apoptotic endothelial cell phenotype in sepsis [ 1, 46].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com