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Here we study the latter, which are precisely the designs with constant replication and block size.
In this case, the size of the compartment would be doubled in each step even for constant replication rates.
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Changing conditions such as temperature variations and/or alterations in the environment's resource composition lead to both non-constant replication and decay rates of the molecules.
The constant viral replication in conjunction with impaired IFNL3 mediated regulatory activity amplifies IFN-α-mediated ISG expression further.
Constant virus replication in CD4 T lymphocytes initiates progressive immune defects and finally, after 6 to 10 years, results in acquired immunodeficiency syndrome (AIDS) and death.
As shown in Table 2, false discovery rate (FDR) is well controlled for all methods when mutation rate is assumed constant across replication timing region and expression level.
Since we can neglect nucleotide errors, we assume a faithful reproduction of the genetic material when the copy number of each chromosome in a sequence (two, for example, in a diploid cell) is kept constant during replication, both numerically (number of physically distinct whole chromosomes or fragments) and structurally (translocations, deletions and amplifications of DNA).
Cells have evolved several mechanisms to deal with the constant challenge of replication stress.
On the other hand, gBGC affects the probability of allele fixation, whereas the global probability p nc of error noncorrection and allele fixation is supposed to be constant in the replication model.
Given the experimental design, this procedure enabled us to examine the effects of temporal variance of disturbance while keeping intensity and spatial extent constant, so to maximize replication for the main test of interest (n = 18).
We now change the degradation rate itself by an additive constant, and keep the replication rate constant.
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