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The expression they derived for maintaining constant image quality did not include a height term.
De Groot et al. [7] demonstrated that the use of a dedicated FDG activity protocol, depending quadratically on a patient's body weight, delivers a constant image quality across patients in several weight categories.
Thus, a different relationship between dose and body mass or a different patient-dependent parameter, e.g. body mass index (BMI) or lean mass, might be required to obtain an even more constant image quality [2, 3].
From Equation 5, it follows that the dose regimen described by Equation 6 should result in a more constant image quality for FDG whole-body PET scans, independent of the patient-dependent parameter: A · t = SNR acc a · p − d 2 = SNR acc a 2 · p 2 d. (6).
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The FDG activity formula presented in this paper provides a constant and standardized PET image quality for all patients [7].
Combination of Equations 3 and 4 shows that SNRL, and hence the image quality, is constant if A · t · a · p − d = constant.
Both simulations and clinical observations confirm that image quality remains constant across patients when this quadratic dose regimen is used.
This method enables to keep the image quality almost constant beyond the resolution limit for thick samples made of gold nanoparticles in water.
A quadratic relation between FDG dose and the patient's body mass is recommended as both simulations and clinical observations confirm that image quality remains constant across patients when this dose regimen is used.
Diagnostic ultrasound (US) is a medical imaging technique which, since its introduction in clinical practice at the end of the 1960s, has seen continuous improvement in image quality and constant growth in number of examinations perfromed and variety of clinical applications.
Analyzing the data, we determined that a quadratic relation between the patient's body mass and administered dose should result in a more constant SNRL, i.e. an image quality that is less dependent of the patient's body mass.
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